[4-Chloro-6-(23-Xylidino)-2-Pyrimidinylthio]Acetic Acid 99.0%(HPLC)
99.0%(HPLC)
Synonym: Pirinixic Acid
Linear Formula:
C14H14ClN3O2S
Molecular Weight: 323.80g/mol
CAS Number: 50892-23-4
Properties
| Vapour pressure | 0.0±1.4 mmHg at 25℃ |
| Assay Purity | >99%(HPLC) |
| Refractive index | 1.658 |
| B pt. | 514.4℃ at 760 mmHg |
| M pt. | 155℃ |
| Density | 1.42g/cm3 |
Safety Information
| Hazard Statement(s) | H302 - H315 - H319 - H335 - H350 |
| Precautionary Statement | P201 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 - P308 + P313 |
| Symbol |
|
| Signal word | Danger |
| HS Code | 2933599090 |
| Flash point | 264.9℃ |
| Storage Temp. | Store at room temperature |
| Storage Class | 3 |
| Packaging | Glass Bottle |
| UN Number | 1993 |
Description
Application
WY-14643 has been used as a positive control for transfection and luciferase assay to stimulate bone marrowderived macrophages (BMDM) for autophagic flux analysis to analyze the regulation of fatty acid metabolism-immune nexus (FAMIN) expression in cell culture.
Purpose
For R&D use onlynot for drug household or other uses.
General Description
WY-14643 prevents lipopolysaccharide (LPS)-induced inflammation in synovial fibroblasts. It protects cortical neurons from pro-inflammatory mediator-induced cell injuries. WY-14643 has inhibitory effects on pro-inflammatory responses in microglia. It improves oxido-nitrosative stress in disease models and reduces the generation of reactive oxygen species (ROS) nitric oxide (NO) and lipid peroxidation end-products in the brain.
Documents
| SDS |
| COA |
| Specification |
| Bulk quote order form |