3-Methyladenine
Synonym: 6-Amino-3-methylpurine
Linear Formula:
C6H7N5
Molecular Weight: 149.16g/mol
CAS Number: 5142-23-4
Properties
| Vapour pressure | 0.0±0.5 mmHg at 25℃ |
| Refractive index | 1.807 |
| B pt. | 240.1℃ at 760 mmHg |
| M pt. | 300℃(dec.) |
| Density | 1.6g/cm3 |
Safety Information
| Hazard Statement(s) | H315-H319 |
| Precautionary Statement | P264-P280-P302 + P352-P337 + P313-P305 + P351 + P338 -P362 + P364-P332 + P313 |
| Symbol |
|
| Signal word | Warning |
| HS Code | 2933990090 |
| Flash point | 99℃ |
| Storage Temp. | Store at +4℃ |
| Storage Class | 8 |
| Packaging | Poly Bottle |
| UN Number | 3261 |
Description
Application
3-Methyladenine (3-MA) is used to inhibit and study the mechanism of autophagy (lysosomal self-degradation) and apoptosis under various conditions. 3-MA inhibits autophagy by blocking autophagosome formation via the inhibition of type III Phosphatidylinositol 3-kinases (PI-3K). For use as an autophagy inhibitor 3-MA is typically used at a concentration of 5 mM.
Purpose
For R&D use onlynot for drug household or other uses.
General Description
3-MA inhibits autophagy by blocking autophagosome formation via the inhibition of type III Phosphatidylinositol 3-kinases (PI-3K). For use as an autophagy inhibitor 3-MA is typically used at a concentration of 5 mM.
Documents
| SDS |
| COA |
| Specification |
| Bulk quote order form |