Novobiocin Sodium Salt


Synonym:  Novobiocin sodium
Linear Formula:  C31H35N2NaO11
Molecular Weight:  634.61g/mol
CAS Number: 1476-53-5

Properties

Water Solubility Soluble
B pt. 848.2℃ at 760mmHg
M pt. 215-220℃
Density 1.42g/cm3

Safety Information

Hazard Statement(s) H302 - H317 - H319
Precautionary Statement  P261 - P264 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
Symbol
Signal word Warning
Flash point 466.8℃
Storage Temp. 2-8℃
Packaging Glass Bottle

Description

Application
Novobiocin an inhibitor of Hsp90 is used to study heat shock protein inhibition and to produce positively supercoiled plasmid DNA. For the production of positively supercoiled plasmid DNA. Inhibitor of bacterial DNA gyrase and eukaryotic DNA topoisomerase. Inhibitor of retrovirus RNA-dependent DNA-polymerase.

Purpose
For R&D use onlynot for drug household or other uses.

General Description
Novobiocin is an antibiotic that acts as an inhibitor of bacterial DNA gyrase and eukaryotic DNA topoisomerase. Studies show that Novobiocin is also an inhibitor of retrovirus RNA-dependent DNA-polymerase. Novobiocin is used in the production of positively supercoiled plasmid DNA.