Spironolactone was added to rat diet to study the effect of long-term spironolactone use on renal function.

For R&D use onlynot for drug household or other uses.

It is a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics used primarily to treat ascites in patients with liver disease low-renin hypertension hypokalemia and Conns syndrome.