2-Aminoethyl Diphenylborinate 98.0%(HPLC)

98.0%(HPLC)


Linear Formula:  C14H16BNO
Molecular Weight:  225.10g/mol
CAS Number: 524-95-8

Properties

Vapour pressure 0.0±0.7 mmHg at 25℃
Assay Purity >98%(HPLC)
Refractive index 1.56
B pt. 325.3℃ at 760 mmHg
M pt. 190℃
Density 1.04 g/cm3

Safety Information

Hazard Statement(s) H302-H315-H319
Precautionary Statement  P501-P270-P264-P280-P302 + P352-P337 + P313-P305 + P351 + P338-P362 + P364-P332 + P313-P301 + P312 + P330
Symbol
Signal word Warning
HS Code 2931900090
Flash point 150.6℃
Storage Temp. 2-8℃
Storage Class 3
Packaging Glass Bottle
UN Number 3272

Description

Application
Reactant for Preparation of apoptotic inducers Activator of the Orai3 (ORAI calcium release-activated calcium modulator 3) protein Inhibits Ca2 influx through transient receptor potential 2 channels in rat dorsal root ganglion neurons Membrane-permeable SOCE (store operated calcuym entry) inhibitor.

Purpose
For R&D use onlynot for drug household or other uses.

General Description
2-Aminoethoxydiphenyl borate (2-APB) is a chemical that acts to inhibit both IP3 receptors and TRP channels (although it activates TRPV1 TRPV2 & TRPV3 at higher concentrations). In research it is used to manipulate intracellular release of calcium ions (Ca2) and modify TRP channel activity although there its lack of specific effects make it less than ideal under some circumstances