Cortisone has been used to validate a 1-HSD1 (11-hydroxysteroid dehydrogenase type 1) inhibitor to study the sensitivity of erythropoietic and granulopoietic progenitor cells to cortisone in the determination of rates of cortisol oxidation by 11HSD.

For R&D use onlynot for drug household or other uses.

Cortisone (17-hydroxy-11-dehydrocorticosterone) is a 21-carbon steroid hormone. It is one of the main hormones released by the adrenal gland in response to stress. In chemical structure it is a corticosteroid closely related to cortisol. It is used to treat a variety of ailments and can be administered intravenously orally intraarticularly (into a joint) or transcutaneously. Cortisone suppresses the immune system thus reducing inflammation and attendant pain and swelling at the site of the injury. Risks exist in particular in the long-term use of cortisone.