Estrone 98.0%(HPLC)

98.0%(HPLC)


Linear Formula:  C18H22O2
Molecular Weight:  270.37g/mol
CAS Number: 53-16-7

Properties

Vapour pressure 0.0±1.1 mmHg at 25℃
Water Solubility Insoluble
Assay Purity >98%(HPLC)
Refractive index 1.587
B pt. 445.2℃ at 760 mmHg
M pt. 258-260 ℃(lit.)
Density 1.164 g/cm3

Safety Information

Hazard Statement(s) H360-H350
Precautionary Statement  P501-P202-P201-P280-P308 + P313-P405
Symbol
Signal word Danger
HS Code 2937290090
Flash point 189.7℃
Storage Temp. Store at room temperature
Storage Class 8
Packaging Glass Bottle
UN Number 1230

Description

Application
Estrone has been used as medium supplement for hormone based degranulation studies of natural killer cells as an endocrine disrupting compound for screening bacterial biosensor in toxic water. as medium component for monitoring fatty acid synthase (FASN) activity in breast adenocarcinoma cell lines

Purpose
For R&D use onlynot for drug household or other uses.

General Description
Estrone is a weak form of estrogen and exists as estrone sulphate.[1]Estrone is a luteolytic estrogen produced by the corpus luteum.[2]In the follicle estrone is synthesized from androstenedione by the action of cytochrome P450 aromatase.