Ribostamycin Sulfate 90.0%
90.0%
Synonym: Ribostamycin sulfate salt
Linear Formula:
C17H34N4O10·xH2SO4
Molecular Weight: 552.55g/mol
CAS Number: 53797-35-6
Properties
| Assay Purity | >90% |
| B pt. | 907.6℃ at 760 mmHg |
| M pt. | 180℃ |
| Density | 1.6g/cm3 |
Safety Information
| Hazard Statement(s) | H312 + H332 - H360 |
| Precautionary Statement | P201 - P202 - P280 - P302 + P352 + P312 - P304 + P340 + P312 - P308 + P313 |
| Symbol |
|
| Signal word | Danger |
| Flash point | 502.7℃ |
| Storage Temp. | 0-10℃ |
| Packaging | Glass Bottle |
Description
Application
Ribostamycin is a broad-spectrum antimicrobial isolated fromStreptomyces ribosifidicus. It is used in pharmacokinetic and nephrotoxicity studies
Purpose
For R&D use onlynot for drug household or other uses.
General Description
Ribostamycin is an aminoglycoside-aminocyclitol antibiotic isolated from a streptomycete Streptomyces ribosidificus originally identified in a soil sample from Tsu City of Mie Prefecture in Japan. It is made up of 3 ring subunits 2-deoxystreptamine (DOS) neosamine C and ribose. Ribostamycin along with other aminoglycosides with the DOS subunit is an important broad-spectrum antibiotic with important use against human immunodeficiency virus and is considered a critically important antimicrobial by the World Health Organization. Resistance against aminoglycoside antibiotics such as ribostamycin is a growing concern. The resistant bacteria contain enzymes that modify the structure through phosphorylation adenylation and acetylation and prevent the antibiotic from being able to interact with the bacterial ribosomal RNAs.
Documents
| SDS |
| COA |
| Specification |
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