Ribostamycin Sulfate 90.0%

90.0%


Linear Formula:  C17H34N4O10·xH2SO4
Molecular Weight:  552.55g/mol
CAS Number: 53797-35-6

Properties

Assay Purity >90%
B pt. 907.6℃ at 760 mmHg
M pt. 180℃
Density 1.6g/cm3

Safety Information

Hazard Statement(s) H312 + H332 - H360
Precautionary Statement  P201 - P202 - P280 - P302 + P352 + P312 - P304 + P340 + P312 - P308 + P313
Symbol
Signal word Danger
Flash point 502.7℃
Storage Temp. 0-10℃
Packaging Glass Bottle

Description

Application
Ribostamycin is a broad-spectrum antimicrobial isolated fromStreptomyces ribosifidicus. It is used in pharmacokinetic and nephrotoxicity studies

Purpose
For R&D use onlynot for drug household or other uses.

General Description
Ribostamycin is an aminoglycoside-aminocyclitol antibiotic isolated from a streptomycete Streptomyces ribosidificus originally identified in a soil sample from Tsu City of Mie Prefecture in Japan. It is made up of 3 ring subunits 2-deoxystreptamine (DOS) neosamine C and ribose. Ribostamycin along with other aminoglycosides with the DOS subunit is an important broad-spectrum antibiotic with important use against human immunodeficiency virus and is considered a critically important antimicrobial by the World Health Organization. Resistance against aminoglycoside antibiotics such as ribostamycin is a growing concern. The resistant bacteria contain enzymes that modify the structure through phosphorylation adenylation and acetylation and prevent the antibiotic from being able to interact with the bacterial ribosomal RNAs.