Methyldopa (L--Methyl-34-dihydroxyphenylalanine Aldomet Aldoril Dopamet Dopegyt etc.) is a centrally acting antihypertensive agent. It is metabolized to alpha-methylnorepinephrine in the brain and this compound is thought to activate central alpha-2 adrenergic receptors (Gerber 1990). Being a selective agonist for 2 adrenergic receptors psychoactive drug is used as a sympatholytic or antihypertensive. Its use is now mostly deprecated following the introduction of alternative safer classes of agents. However it continues to have a role in otherwise difficult to treat hypertension and gestational hypertension (previously known as pregnancy-induced hypertension (PIH)).

For R&D use onlynot for drug household or other uses.