N-Succinimidyl 6-Maleimidohexanoate [Cross-Linking Reagent] 98.0%
98.0%
Synonym: N-(6-Maleimidocaproyloxy)succinimide
Linear Formula:
C14H16N2O6
Molecular Weight: 308.29g/mol
CAS Number: 55750-63-5
Properties
| Vapour pressure | 0.0±1.2 mmHg at 25℃ |
| Assay Purity | >98% |
| Refractive index | 1.577 |
| B pt. | 480.6℃ at 760 mmHg |
| M pt. | 71℃ |
| Density | 1.4 g/cm3 |
Safety Information
| Hazard Statement(s) | H315-H319 |
| Precautionary Statement | P264-P280-P302 + P352 -P337 + P313-P305 + P351 + P338-P362 + P364-P332 + P313 |
| Symbol |
|
| Signal word | Warning |
| HS Code | 2925190090 |
| Flash point | 244.5±29.3℃ |
| Storage Temp. | '20℃ |
| Packaging | Amber Glass bottle |
Description
Application
6-Maleimidohexanoic acidN-hydroxysuccinimide ester can be used in Synthesis of maleimide-activated carbohydrates for site-specific glycosylation of cysteine-containing peptides and proteins via maleimide-thiol ligation reaction. Synthesis of a glucuronide prodrug of doxorubicin bearing a maleimide side chain as an antitumor agent. Cross-linking oligonucleotides with the amino groups on the substrate to fabricate DNA microarrays.
Purpose
For R&D use onlynot for drug household or other uses.
General Description
6-Maleimidohexanoic acid N-hydroxysuccinimide ester(ECMS) is a useful protective group in antibody drug conjugates.
Documents
| SDS |
| COA |
| Specification |
| Bulk quote order form |