5Alpha-Pregnane-320-Dione 98.0%(GC)

98.0%(GC)


Linear Formula:  C21H32O2
Molecular Weight:  316.49g/mol
CAS Number: 566-65-4

Properties

Vapour pressure 0.0±1.0 mmHg at 25℃
Assay Purity >98%(GC)
Refractive index 1.516
B pt. 429.2℃
M pt. 204℃
Density 1.048 g/cm3

Safety Information

Symbol
Flash point 160.3℃
Storage Temp. Store at Room Temperature
Packaging Poly Bottle

Description

Purpose
For R&D use onlynot for drug household or other uses.

General Description
5-Dihydroprogesterone (5-DHP) also known as 5-pregnan-320-dione is an endogenous progestogen and neurosteroid that is synthesized from progesterone. It is also an intermediate in the synthesis of allopregnanolone and isopregnanolone from progesterone. 5-DHP is an agonist of the progesterone receptor and a positive allosteric modulator of the GABAA receptor (albeit with an affinity for this receptor that is regarded as relatively low (in comparison to 3-hydroxylated progesterone metabolites such as allopregnanolone and pregnanolone)).