Probenecid has been used as a component of phenol red free Hanks buffer for Intracellular Ca2-mobilization assay as a component of calcium sensitive dye for calcium mobilization Studies as a supplement in Hanks balanced salt solution (HBSS) assay buffer. Useful as an inhibitor of the organic anion transporter MRP.

For R&D use onlynot for drug household or other uses.

Probenecid also sold under the brandname Probalan is a medication that increases uric acid excretion in the urine. It is primarily used in treating gout and hyperuricemia. Probenecid was developed as an alternative to caronamide to competitively inhibit renal excretion of some drugs thereby increasing their plasma concentration and prolonging their effects.