Oncrasin 1 95.0%(HPLC)

95.0%(HPLC)


Linear Formula:  C16H12ClNO
Molecular Weight:  269.73g/mol
CAS Number: 75629-57-1

Properties

Assay Purity >95%(HPLC)
Refractive index 1.62
B pt. 465.5℃ at 760 mmHg
M pt. 117℃
Density 1.21g/cm3

Safety Information

Hazard Statement(s) H315-H319
Precautionary Statement  P264-P280-P302 + P352-P337 + P313-P305 + P351 + P338-P362 + P364-P332 + P313
Symbol
Signal word Warning
HS Code 2933990090
Flash point 235.3℃
Storage Temp. 0-10℃
Packaging Glass Bottle

Description

Recommended products
4-(Methylthio)Butanol 99%

Application
Oncrasin-1 is a potent and effective anticancer inhibitor that kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrations also led to abnormal aggregationof PKC in nucleus of sensitive cells but not in resistant cells.IC50 value 1.0 M(A549 K-ras 12H and p53 Wt) [1]Target human lung cancer cells with K-Ras mutation K-RasPKCiota pathway inhibitorin vitro effectively kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrations.

Purpose
For R&D use onlynot for drug household or other uses.

Documents

COA
Not Available
 
SDS
COA
Specification
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