Prostaglandin E2 PurCert Secondary Reference Standard (CRM) [Includes all characterization data]

PurCert


Properties

Assay Purity >= 98 %
Refractive index n20/D 1.6120 
B pt. 406.07°C
M pt. 66-68°C
Density 1.0601
Form Solid

Safety Information

Hazard Statement(s) H302,H360FD
Precautionary Statement  P202 - P264 - P270 - P280 - P301 + P312 - P308 + P313
GHS Pictogram
Signal word Danger
HS Code 29375000
Storage Temp. -20 °C
Storage Class 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Description

Application
PGE2 is used medically to induce labor and cervical ripening as dinoprostone gel or insert and serves as a research tool for studying inflammation pain fever smooth muscle contraction and gastrointestinal mucosal protection.

Purpose
It mediates physiological processes including vasodilation smooth muscle relaxation or contraction via EP1-4 receptors inflammation renal blood flow regulation and inhibition of gastric acid secretion through increased cAMP and calcium signaling pathw

General Description
Prostaglandin E2 (PGE2) also known as dinoprostone is a lipid compound with the molecular formula CHO and molecular weight of 352.47 gmol featuring a cyclopentanone ring with hydroxyl groups a carboxylic acid chain and a side chain with a double bond and hydroxyl synthesized from arachidonic acid via cyclooxygenase enzymes.