It is administered orally in tablets capsules or suspensions to treat infections including uncomplicated gonorrhea pharyngitis tonsillitis acute exacerbations of chronic bronchitis urinary tract infections and otitis media caused by susceptible Gram-negative and Gram-positive bacteria.

Cefixime trihydrate inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins effective against pathogens like Streptococcus pneumoniae Haemophilus influenzae Moraxella catarrhalis and Neisseria gonorrhoeae with enhanced -lact

Cefixime trihydrate is the trihydrate form of the third-generation cephalosporin antibiotic cefixime with molecular formula CHNOS (MW 507.50 gmol CAS 125110-14-7) featuring a -lactam ring fused to a dihydrothiazine ring with a (2Z)-2-(2-amino-4-thiazolyl)-2-[(carboxymethoxy)imino]acetyl side chain at C-7 and a vinyl group at C-3 appearing as a white to off-white crystalline powder.