Rifabutin 98.0%(HPLC)

98.0%(HPLC)


Synonym:  Ansamycin
Linear Formula:  C46H62N4O11
Molecular Weight:  847.02g/mol
CAS Number: 72559-06-9

Properties

Vapour pressure 0.0±0.3 mmHg at 25℃
Water Solubility Practically insoluble
Assay Purity >98%(HPLC)
Refractive index 1.623
B pt. 969.589℃ at 760 mmHg
M pt. 156℃
Density 1.339g/cm3

Safety Information

Symbol
HS Code 2941903000
Flash point 540.188℃
Storage Temp. ?20℃
Packaging Glass Bottle

Description

Recommended products
Diethylene Glycol 2-Bromoethyl Methyl Ether 94.0%(GC)

Application
Rifabutin (Rfb) is a bactericidal antibiotic drug primarily used in the treatment of tuberculosis. The drug is a semi-synthetic derivative of rifamycin S. Its effect is based on blocking the DNA-dependent RNA-polymerase of the bacteria. It is effective against Gram-positive and some Gram-negative bacteria but also against the highly resistant mycobacteria e.g. Mycobacterium tuberculosis M. leprae and M. avium intracellulare.

Purpose
For R&D use onlynot for drug household or other uses.

General Description
Rifabutin is primarily bactericidal antibiotic drug used to treat tuberculosis. Its effect on bacteria is based on the DNA-dependent RNA polymerase blocking drug rifamycin S. a semi-synthetic derivative. It is effective for example in highly resistant mycobacteria Gram-positive bacteria (and some are effective against Gram-negative bacteria) but also against Mycobacterium tuberculosis M. leprae and M. avium intracellulare.Rifabutin is an antibiotic antitumor. Rifabutin interferes with HSP-90 molecular chaperone enhances ubiquitination and protein degradation and inactivates bacterial RNA polymerase.

Documents

COA
Not Available
 
SDS
COA
Specification
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