Mestranol 98.0%(HPLC)
98.0%(HPLC)
Synonym: 17?-Ethynylestradiol 3-Methyl Ether
Linear Formula:
C21H26O2
Molecular Weight: 310.44g/mol
CAS Number: 72-33-3
Properties
| Vapour pressure | 0.0±1.1 mmHg at 25℃ |
| Water Solubility | Insoluble |
| Assay Purity | >98%(HPLC) |
| Refractive index | 1.591 |
| B pt. | 464.1℃ at 760 mmHg |
| M pt. | 151℃ |
| Density | 0.905g/cm3 |
Safety Information
| Hazard Statement(s) | H315 - H319 - H351 |
| Precautionary Statement | P201 - P302 + P352 - P305 + P351 + P338 - P308 + P313 |
| Symbol |
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| Signal word | Warning |
| Flash point | 224.1℃ |
| Storage Temp. | Store at room temperature. |
| Packaging | Amber Glass Bottle |
Description
Recommended products
9-Anthracenecarboxylic Acid 97.0%(GC)
Application
Mestranol (INN USAN BAN JAN) (brand names Devocin Ovastol Tranel) also known as ethinyl estradiol methyl ether (EEME) is a synthetic steroidal estrogen that has been widely used medically. It was employed as the estrogen component in many of the first oral contraceptives such as mestranolnoretynodrel (brand names Enovid Enavid) and is still in use today. It was also a component of Ortho-Novin Femigen and Norbiogest. In addition to its use as an oral contraceptive mestranol has been used as a component of hormone replacement therapy.
Purpose
For R&D use onlynot for drug household or other uses.
General Description
Mestranol is the 3-methyl ether of ethinylestradiol. It was the estrogen used in many of the first oral contraceptives.Target Estrogen ReceptorERRMestranol is absorbed very rapidly from the digestive tract and maximum plasma levels are attained in 1-4 hours the majority at 1-2 hours. Detectable levels of mestranol are present 24 hours postingestion in 58% of subjects after a 50 g dose and in 79% after a 100 g dose. At all dose levels highest plasma mestranol levels and area under the curve of plasma levels (AUC) occurred in Sri Lankan women and lowest plasma levels in Nigerian women even when corrected for body surface differences
Documents
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