Moclobemide 98.0%(HPLC)
98.0%(HPLC)
Properties
| Vapour pressure | 0.0±1.1 mmHg at 25℃ |
| Assay Purity | >98%(HPLC) |
| Refractive index | 1.55 |
| B pt. | 447.7℃ at 760 mmHg |
| M pt. | 138℃ |
| Density | 1.206 g/cm3 |
Safety Information
| Hazard Statement(s) | H302-H315-H319 |
| Precautionary Statement | P501-P270-P264-P280-P302 + P352-P337 + P313-P305 + P351 + P338-P362 + P364-P332 + P313-P301 + P312 + P330 |
| Symbol |
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| Signal word | Warning |
| Flash point | 224.6℃ |
| Storage Temp. | Store at room temperature. |
| Storage Class | 6.1(b) |
| Packaging | Glass Bottle |
| UN Number | 3249 |
Description
Recommended products
1-Methylindole-3-Carboxaldehyde 98%
Application
Moclobemide(Ro111163) is a reversible monoamine oxidase inhibitor (MAOI) selective for isoform A (RIMA) used to treat major depressive disorder.Target Monoamine OxidaseMoclobemide orally administered 2 hours before decapitation preferentially inhibits MAO-A and PEA in rat brain with ED50 of 7.6 molkg and 78 molkg respectively. Moclobemide orally administered 2 hours before decapitation preferentially inhibits MAO-A and PEA in rat liver with ED50 of 8.4 molkg and 6.6 molkg respectively. Moclobemide (0.1 mM) which inhibits brain MAO-A activity by over 80% does not affect benzylamine oxidase (rat heart) and diamine oxidase (rat small intestine) activity in vitro.
Purpose
For R&D use onlynot for drug household or other uses.
Documents
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