Trifluorothymidine 98.0%(HPLC)

98.0%(HPLC)


Linear Formula:  C10H11F3N2O5
Molecular Weight:  296.20g/mol
CAS Number: 70-00-8

Properties

Water Solubility Soluble
Assay Purity >98%(HPLC)
Refractive index 1.534
M pt. 189℃
Density 1.646g/cm3

Safety Information

Symbol
Storage Temp. ?20℃
Storage Class 3
Packaging Bottomless glass Bottle
UN Number 1993

Description

Recommended products
2-Bromo-4-Fluoro-1-Nitrobenzene 98.0%(GC)

Application
Trifluorothymidine (Trifluridine TFT) is a substrate used to study the specificity and kinetics of thymidine kinase(s). TFT after phosphorylation may be incorporated into DNA where is induces DNA-damage consequently TFT is useful for studies of DNA repair mechanisms. TFT may also be used to study mechanisms of inhibition of thymidylate synthase(s).

Purpose
For R&D use onlynot for drug household or other uses.

General Description
Trifluridine is an irreversible thymidylate synthase inhibitor and thereby suppresses DNA synthesis. Trifluridine is an antiviral drug for herpes simplex virus (HSV) infection.

Documents

COA
Not Available
 
SDS
COA
Specification
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