Trifluorothymidine 98.0%(HPLC)
98.0%(HPLC)
Synonym: ?,?,?-Trifluorothymidine
Linear Formula:
C10H11F3N2O5
Molecular Weight: 296.20g/mol
CAS Number: 70-00-8
Properties
| Water Solubility | Soluble |
| Assay Purity | >98%(HPLC) |
| Refractive index | 1.534 |
| M pt. | 189℃ |
| Density | 1.646g/cm3 |
Safety Information
| Symbol | |
| Storage Temp. | ?20℃ |
| Storage Class | 3 |
| Packaging | Bottomless glass Bottle |
| UN Number | 1993 |
Description
Recommended products
2-Bromo-4-Fluoro-1-Nitrobenzene 98.0%(GC)
Application
Trifluorothymidine (Trifluridine TFT) is a substrate used to study the specificity and kinetics of thymidine kinase(s). TFT after phosphorylation may be incorporated into DNA where is induces DNA-damage consequently TFT is useful for studies of DNA repair mechanisms. TFT may also be used to study mechanisms of inhibition of thymidylate synthase(s).
Purpose
For R&D use onlynot for drug household or other uses.
General Description
Trifluridine is an irreversible thymidylate synthase inhibitor and thereby suppresses DNA synthesis. Trifluridine is an antiviral drug for herpes simplex virus (HSV) infection.
Documents
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