Cis-4-Hydroxy-L-Proline 97.0%

97.0%


Linear Formula:  C5H9NO3
Molecular Weight:  131.13g/mol
CAS Number: 618-27-9

Properties

Vapour pressure 0.0±1.8 mmHg at 25℃
Water Solubility Soluble
Assay Purity >97%
Refractive index 1.54
B pt. 355.2℃ at 760 mmHg
M pt. 241℃
Density 1.395 g/cm3

Safety Information

Symbol
HS Code 2933990090
Flash point 168.6℃
Storage Temp. Store at room temperature.
Packaging Glass Bottle

Description

Recommended products
3-Chlorobenzamide 98.0%

Application
cis-4-Hydroxy-L-proline (CHP) is a proline analog that inhibits collagen synthesis and has been used as an anticancer compound.[2]CHP blocked myotube formation and expression of sarcomeric myosin heavy chain in C2C12 murine skeletal muscle cells.[1]CHP inhibited proliferation of murine Panc02 pancreatic carcinoma cell line[4]and rat pancreatic carcinoma cell line DSL6A.

Purpose
For R&D use onlynot for drug household or other uses.

General Description
Hydroxyprolines are valuable chiral building blocks for organic synthesis of pharmaceuticals. Several microorganisms producing proline trans-4- and cis-3-hydroxylase were discovered and these enzymes were applied to the industrial production of trans-4- and cis-3-hydroxy-L-proline.

Documents

COA
Not Available
 
SDS
COA
Specification
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