Simvastatin 97.0%(HPLC)

97.0%(HPLC)


Properties

Vapour pressure 0.0±3.5 mmHg at 25℃
Assay Purity >97%(HPLC)
Refractive index 1.53
B pt. 564.9℃ at 760 mmHg
M pt. 134℃
Density 1.11 g/cm3

Safety Information

Hazard Statement(s) H361d
Precautionary Statement  P201 - P202 - P280 - P308 + P313 - P405 - P501
Symbol
Signal word Warning
Flash point 184.8℃
Storage Temp. 0-6℃
Storage Class 9
Packaging Poly Bottle
UN Number 3077

Description

Recommended products
2-Chloro-NN-Diethylacetamide 97%

Application
Simvastatin has been used as an inhibitor of HMG CoA reductase (HMGCR) to study its effects on epithelial to mesenchymal transition (EMT) and the prognosis of patients with lung adenocarcinoma in in vivo studies to test its effect on brain tumorinitiating cells (BTIC) viability and cell proliferation to study the role of adenosine triphosphate (ATP)-binding cassette transporter A7 in phagocytosis of Jurkat cells to study the effect on endothelial dysfunction and inflammation in mice.

Purpose
For R&D use onlynot for drug household or other uses.

General Description
Simvastatin is a prodrug. Simvastatin is a semisynthetic derivativeanalog of lovastatin. Simvastatin is insoluble in water but is soluble in polar organic solvents.