Diphenyl Phosphorochloridate 97%

FR180204 has been used as ERK inhibitor to block extracellular-signal-regulated kinase (ERK) in order to validate whether homeobox B7 (HOXB7) regulates the migration and proliferation process via AKTmitogen-activated protein kinases (MAPK) signaling of extracellular-signal-regulated kinase (ERK) to study the effects of signaling pathway inhibitors on differentiation and cell traction stress to determine if phosphorylation of this signaling protein is essential for mesenchymal stromal cell (MSC) derived therapeutic efficacy.

For R&D use onlynot for drug household or other uses.

FR180204 is a potent cell-permeable ATP-competitive inhibitor of ERK1 and ERK2 (mitogen-activated protein kinase (MAPK)extracellular-signal-regulated kinases (ERK) 12).