Loteprednol Etabonate 98.0%(HPLC)

98.0%(HPLC)


Properties

Vapour pressure 0.0±3.9 mmHg at 25℃
Water Solubility Insoluble
Assay Purity >98%(HPLC)
Refractive index 1.571
B pt. 600.1℃ at 760 mmHg
M pt. 225℃(dec.)
Density 1.31 g/cm3

Safety Information

Hazard Statement(s) H361-H413
Precautionary Statement  P501-P273-P202-P201-P280-P308 + P313 -P405
Symbol
Signal word Warning
HS Code 2937229000
Flash point 316.7℃
Storage Temp. ?20℃
Packaging Glass Bottle

Description

Recommended products
5-Cyanophthalide 98.0%(HPLC)

Application
Loteprednol (as the ester loteprednol etabonate) is a corticosteroid used to treat inflammations of the eye. It is marketed by Bausch and Lomb as Lotemax.

Purpose
For R&D use onlynot for drug household or other uses.

General Description
Loteprednol Etabonate is an anti-inflammatory corticosteroid used in optometry and ophthalmology.IC50 ValueTarget Glucocorticoid Receptorin vitroin vivo Intravenous administration of loteprednol etabonate (5 mgkg) to dogs revealed a terminal half-life of 2.8 h a volume of distribution of 3.7 Lkg and a total body clearance of 0.9 Lhkg. Intact loteprednol etabonate was not detectable in the urine.