Cyclosporin A 97.0%(HPLC)

97.0%(HPLC)


Synonym:  Cyclosporin
Linear Formula:  C62H111N11O12
Molecular Weight:  1202.61 g/mol
CAS Number: 59865-13-3

Properties

Vapour pressure 0.0±0.6 mmHg at 25℃
Assay Purity >97%(HPLC)
Refractive index 1.468
B pt. 1293.8℃ at 760 mmHg
M pt. 151℃
Density 1.016 g/cm3

Safety Information

Hazard Statement(s) H302 - H350 - H360FD
Precautionary Statement  P201 - P301 + P312 + P330 - P308 + P313
Symbol
Signal word Danger
HS Code 2941909000
Flash point 736.3℃
Storage Temp. Store at room temperature.
Storage Class 3
Packaging Glass Bottle
UN Number 3295

Description

Recommended products
Nitrofurazone 98.0%(HPLC)(E)

Application
Ciclosporin also spelled cyclosporine is an immunosuppressant drug widely used in organ transplantation to prevent rejection. It reduces the activity of the immune system by interfering with the activity and growth of T cells.

Purpose
For R&D use onlynot for drug household or other uses.

General Description
It was initially isolated from the fungus Tolypocladium inflatum found in a soil samples in 1969 from Norway by Hans Peter Frey. Most peptides are synthesized by ribosomes but ciclosporin is a cyclic nonribosomal peptide of 11 amino acids and contains a single D-amino acid which is rarely encountered in nature.