Ammonium acetate PurChrom for HPLC 99.0%

Aminopterin (or 4-aminopteroic acid) the 4-amino derivative of folic acid is an antineoplastic drug with immunosuppressive properties often used in chemotherapy.

For R&D use onlynot for drug household or other uses.

Aminopterin is a synthetic derivative of pterin. Aminopterin works as an enzyme inhibitor by competing for the folate binding site of the enzyme dihydrofolate reductase. Its binding affinity for dihydrofolate reductase effectively blocks tetrahydrofolate synthesis. This results in the depletion of nucleotide precursors and inhibition of DNA RNA and protein synthesis.