Niflumic Acid 99%

99%


Linear Formula:  C13H9F3N2O2
Molecular Weight:  282.22g/mol
CAS Number: 4394-00-7

Properties

Vapour pressure 0.0±0.9 mmHg at 25℃
Assay Purity 99+%
Refractive index 1.589
M pt. 204℃
Density 1.449 g/cm3

Safety Information

Hazard Statement(s) H301 - H413
Precautionary Statement  P264 - P270 - P273 - P301 + P310 - P405 - P501
Symbol
Signal word Danger
HS Code 2933399090
Storage Temp. Store under inert gas
Storage Class 6.1
Packaging Glass Bottle
UN Number 2811

Description

Recommended products
Niflumic Acid 99%

Application
Niflumic acid has been used as a chloride channel blocker in mouse olfactory epithelium for odor-induced electroolfactograms (EOGs) measurements to test its analgesic effect on rat dorsal root ganglion neurons post -aminobutyric acid induction as a calcium-activated chloride channel (CaCC) inhibitor in C2C12 myoblasts and also to test its effect on volume-regulated anion channel (VRAC) as an inhibitor of voltage-dependent potassium channel in human embryonic kidney (HEK 293) phoenix cells.

Purpose
For R&D use onlynot for drug household or other uses.

General Description
Niflumic acid is a drug used for joint and muscular pain. It is categorized as an inhibitor of cyclooxygenase-2. In experimental biology it has been employed to inhibit chloride channels. It has also been reported to act on GABA-A and NMDA channels and to block T-type calcium channels.