Romidepsin (CHNOS MW 540.7 gmol) is a naturally derived bicyclic depsipeptide with a disulfide bond appearing as a white to off-white powder soluble in DMSO and acts as a prodrug activated by cellular reduction.

Functions as a histone deacetylase (HDAC) inhibitor to induce cancer cell apoptosis cell cycle arrest and epigenetic modulation by hyperacetylating histones and non-histone proteins.

Romidepsin is a bicyclic depsipeptide HDAC inhibitor derived from Chromobacterium violaceum featuring formula CHNOS (MW 540.7 gmol) with a reducible disulfide bond that activates its binding to class I HDAC enzymes.